Nanostructure refinement and solution

Solution and Suspension Plasma Spraying of Nanostructure Coatings

AIRS: Anytime Iterative Refinement of a Solution

Many exponentially-hard problems can be solved by searching through a space of states to determine a sequence of steps constituting a solution. Algorithms that produce optimal solutions (e.g., shortest path) generally require greater computational resources (e.g., time) than their sub-optimal counterparts. Consequently, many optimal algorithms cannot produce any usable solution when the amount ...

Anytime Solving by Solution Refinement By

Date ACKNOWLEDGMENTS Completing a thesis is impossible to achieve without support. I would like to thank Professor Wheeler Ruml, my thesis advisor, for his guidance and support through the process. His influence in instruction, group research, and personal research is invaluable. I would like to give a special thanks to Ethan Burns who provided the thoughtfully crafted search framework that I u...

Severe plastic deformation of copper by machining: Microstructure refinement and nanostructure evolution with strain

The microstructures of copper chips created by plane strain machining at ambient temperature have been analyzed using transmission electron microscopy (TEM) and orientation imaging microscopy (OIM). The strain imposed in the chips was varied by changing the tool rake angle. Characterization of orthogonal faces of the chips showed the microstructure to be essentially uniform through the chip vol...

Automating crystallographic structure solution and refinement of protein–ligand complexes

High-throughput drug-discovery and mechanistic studies often require the determination of multiple related crystal structures that only differ in the bound ligands, point mutations in the protein sequence and minor conformational changes. If performed manually, solution and refinement requires extensive repetition of the same tasks for each structure. To accelerate this process and minimize man...